Diatonic scales have certain characters, which come from the different combinations of intervals (usually tones and semitones). It's because of the same interval over and over that the chromatic (and whole tone) scale sounds relatively characterless. All chromatic scales are equivalent (i.e. a chromatic scale beginning on G contains the exact same notes as a chromatic scale beginning on Eb, or any other note). Same goes for the whole tone scale, because there is only one interval. The same is not true for diatonic scales.
In a diatonic scale, the different intervals "point" to a root (I don't know the psychology as to why), but when every interval in a scale is the same it's like a flat, featureless terrain, which offers no "landmarks" to give a sense of where you are or where you're going.
To test the power of varying intervals, try going up a semitone when you should have gone up a whole-tone (or vice versa), it kind of throws you, putting a totally different "context" on the melody.
Another example, in Lydian mode, when you're ascending it sounds just like major until you get to the sharpened fourth. I don't know why but when you hit that fourth (going up a whole-tone), there's this incredibly "euphoric" sensation, when compared with the major (going up a semitone) - just from going up an extra semitone!
All the scales and modes have different properties like this, depending on their distribution of intervals, but I think it's hard to say exactly why.