It depends on how the sample sounds, for me... if it's a sample that can be looped, then I definitely have to find another sample for the chorus, similar, but switched up, or I could always sample a piece of the sample for the chorus... if it's chops, I always make sure that I switch it up... if not in the verse, as the song moves, then in the chorus, and If I'm comfortable with repeating a sample over and over again, I have to switch the drum patterns up, so that it sound lively, as opposed to just repetitive and bland... it really depends on what you want to hear, and what will keep you interested in the beat, and little changes like those make a big difference...
"GOD MADE HIS REAL N***** OUT OF DIRT" DONTE of MOOD
"To me, music is: Delving before Moving, Delving while Moving, then Moving without Delving...Nuff Sed." Myself
"A life without goals is a life already lived, which is also a dead life..." Myself
"Frenchi da Urban Poet is now Abstracks the Retrospect"
i luv to talk about it! 
