You can simply drag the windows and icons where you want them and hopefully they will stay there. Basically you have one main screen where the start up graphics and the icons of the HardDrives appear (I'm talking Mac OSX here). I don't know if you really need a second monitor with reason, I do not really use this programm.
For a big sequencing program as Cubase or Logic a second monitor is really helpful, though.
...searching....Aahhh......
.......wait...how does this work?
Glad to be here