you have to forgive me if this sounds weird, but i vaguely remember this problem from back in the day - refill packer conflicting with something that had nothing to do with reason. if im not mistaken it was AOL instant messenger. i do remember for sure there was something else on my computer was stopping it from opening. i just now googled and googled and couldnt find it though.
i would troubleshoot, try opening it in safe mode. or quit processes one by one until it opens
---------- Post added at 02:48 PM ---------- Previous post was at 02:41 PM ----------
make sure refill packer is not in the reason folder, and that you arent trying to save refills to the reason folder